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@kathiejac

I have been on the protocol for three months. The first 2 1/2 on the original protocol and the last 3 weeks on 525. I have nerve pain all over from inside my mouth, to my low back and groin and down both legs.
To date there is no difference, but I have had this for 8 years and doubt that change will happen quickly, so I pledged to go at least 6 months before considering it a wash (but may be longer, we shall see)

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Replies to "I have been on the protocol for three months. The first 2 1/2 on the original..."

Hi @kathiejac, welcome to Mayo Clinic Connect. Thank you for sharing your experience. It also took me a couple of months before seeing any changes but I'm still taking it for the long haul since it seems to have stopped the progression of my PN even though I only have numbness.

Can you let us know if you see any further changes?