My husband is only 43. We have never gone to the Mayo clinic I just found you all because I have felt so distressed and needing to talk with people who would understand. We had an initial diagnosis from an ER doc in our rural hometown that is not known for its medical care. They sent us to the city in a panic saying it was Amyloid Angiopathy. The neurologist in the renowned hospital said no that his brain must have always looked like that from an accident or perhaps Rubella in the womb because "he is too smart and he wouldn't be able to keep a wife if he had that." I think he had a stroke (they did not "detect" one) and possibly the prolonged high BP did some damage. Its confusing because alot of times he does seem ok but he has definatelly changed over time. Like his emotional capacity.