Angiev18, Yes, I did have, and to some extent still do, have local docs who have treated me to the best of their ability. However, in order to do that they had to defend me from some major labs, some get-rich-quick medicos, and assorted quacks. But when I show them the list of signs and wonders, most of them just sort of turn away to defend themselves. My symptoms at age 15 were chest pain and ankylosing spondilitis (I know now.). Middle age, three heart attacks, heart caths every few months. Now, it is the heavy stuff. Heart failure with recovered Ejection Fraction, organomegaly of every interior organ, cerebrum protein deposits showing transmissible Spongiform Encephalopathy, purpura on eyelids, toes, macular skin, cancers of thyroid, pancreas, prostate, lungs, esophagus. Cracking and breaking up teeth, massive eosinophil, flattened area across bridge of nose, chalaisis of eye socket and face, lower lip swelling, Am i doing ok now? Good question. I am still alive, but I can tell I am weakening rapidly. Lot of RA in hands and legs. Well, that's the heavy stuff. Heart wall thicknesses up to 17-18 MM, well past the 12 mm standard. Cutis laxa. Putting out about 2.5-3.0 G of hepatic protein per 24 hours. Leatherized urinary valve requires catheter 6-8 times per day. Most important, I am a fan of OMIM from Johns hopkins, I read everything I can get from Helsinki Univ. Hospital, Mayo, Boston Amyloidosis. And I tell everyone where they can find the info. Anyway, and I have diabetes 2, and get the good shoes from Priority. And put my books and stuff out there for folks to find and read.