As a retired RN, I used a lot of Vistaril for my patients, both in Labor & Delivery (years ago) and with other postop meds in surgical recovery room. I have never heard it referred to or used as an anti-inflammatory drug? It definitely can be used as a great antihistamine and like so many of the older antihistamines, can have a mild sedative effect. (Great when you are itching from who knows what!) I know it is used for people who have been diagnosed for chronic hives/urticaria. Nice that it helps you feel better!