YES! LDN was a huge game changer for me with my autoimmune symptoms. I started out on 1mg then got up to 3mg.
Unfortunately, I had to get a new primary care provider who rolled her eyes at it and refuses to prescribe it for me and now my symptoms are so bad that I'm almost totally disabled.
I had my prescription filled at a local compounding pharmacy.
The only side effect I had was a temporary mild insomnia that resolved after two weeks.