in Year Nov-2013 my dad was diagnosed with CA colon and was operated straight away and 12cycles FolFox was followed. Oct-2018 due to increase in CEA level to 12 my Dad was again diagnosed with malignant Solitary lesion between the tail of Pancreas and Spleen. It was the reoccurrence...Again operated in Nov-2018 and has been on oral chemo for last 21months now...All went well... Prior to this CEA was only matter of concern as it was 12 before he got operated and now its 5.7. all along his CA19-9 has been well under normal range less than 37... we repeat his blood test every 21days. on 18Sep2020 his CA19-9 was 15 but today we did his routine blood test and to our shock CA19-9 has shot up to 158.9... last PET was done in July and all was fine apart from mild Fdg uptake at the tail of Pancreas and our Onco was not worried for that. My dad never had cancer of Pancreas and now I wonder what made this CA19-9 rise with 21days 10times from 15 to 158..... its frightening... my dad has been through a lot since last 7years now... can anyone help!!!!