I had stem cell (not transplants - from my own fat cells) done on my knee a few years ago. There is a big difference in the stem cell therapy I had, and the stem cell transplant (from human embryonic cells) that people with serious illnesses get. The process for me was PRP (plasma rich platelets, derived from your blood), injected; then the stem cells, then another PRP. It was quite successful for me; it did not eliminate all the pain, but pain was minor. But the problem is that you never know if it will be successful or not. You should check out local practitioners and talk with them - I don't think they can guarantee success. It cost total around $8,000 (one knee) and was not covered by insurance. The reason I had to have a total knee replacement is because last Feb (2019) I fell down hard on my knee tripping over a jut in the sidewalk in the dark. I could have tried again with stem calls, but the cost adds up, plus the uncertainty. Probably your first step is to locate a reputable doctor in your area. There are tons of scams out there so be careful. Then get x-rays and talk with the doctor to see what advice they have. Good doctors will not recommend stem cell therapy on patients if they think it has no chance to work. It also can be done with bone marrow, which is as I understand it a bit more painful to extract, but the recovery is easier. Before you start: do a lot of online reading. Good luck.