I take it and it makes a significant difference in my pain level. It does more for me than morphine, oxycodone or MS Contin (and tons of other meds). I hate when people make statements like “it does nothing for pain”. Because while it may not work for THEM in helping with their pain- it may work different for a different patient. It has helped me a lot and makes a HUGE difference in my pain level. I’ve taken it for years and can’t see not taking it.