@thumperguy I first learned about nebulizing saline as a cure for mac back in 2007. It was being used only in France at that time. I would mention it to my pulmonologists and they would just blow me off because they had never heard of it. It wasn't until I went to the Mayo clinic in 2013 that my dr there suggested I use it. I wasn't surprised that HE knew about it as Mayo is pretty cutting-edge. My mac has tested negative since 2014. If you think about it, the saline makes a lot of sense. Mothers have been making their kids gargle with warm salt water at the first sign of a sore throat. Why? Because the salt kills the germs. Also, meats keep forever when salted as do fish. Salt kills bacteria. As for your question about tolerating the treatment.....that would depend on the condition of your lungs. If they are super inflamed, they may be too fragile for the salt at 7% or even 3%. If you get the 'ok' from your dr that it is safe for you; you can always start out slowly and build up your tolerance for it. Try doing only several puffs, wait a bit, and try some more. I am traveling right now and ran out of my saline 4 days ago. I can feel the krud building up and starting to feel crappy. I will go tomorrow to the CVS up here and have my script transferred. It makes a big difference for me. I hope this helps.