Oh @erikas how I hate to be one of the examples....for something bad lol!!! Actually, I have not tapered down from PMR, but from Mesenteric Panniculitis (MP). Prednisone is a great drug. It really helped me in 2014, but this bout has not been so effective in that when I am able to try to taper down because of the MP, my PMR acts up. If on too high a dose for a long period of time, the esophageal spasms return....not to mention weight gain (I don't think it's ever going down!), moon face, facial hair, mood swings, insomnia etc. etc. I am curious as to this tocilizmab. Does it replace the prednisone or the methotrexate? Or is it a new accompaniment?