I am sorry to hear about your wife, but My own mystery started in September with getting the Shingrix Shot first dose, then second dose in December and I have declined since them. Many, many symptoms, including double vision, nausea and burning throughout the body upon resting which lasted 3 months and that finally went away. Dizzy, loss of balance, weak legs, weak arms, Depression/Anxiety doubled panic attacks every day, and no one can figure out what is wrong. Had brain MRS, cervical spine MRI, EEG, missed two appointments for EMG due to being hospitalized for severe depression panic attacks, etc. Haven't had that problem in years. Also very weak, twitching, muscle spasms. Twitch finally stopped a week or so ago. Have an appointment with a specialist in Atlanta for eyes, don't know what the EMG test will result in but I was an active 78 year old that went to the Y 5 days a week until November when all this started, and all doctors think it's in my head. I know my body, and know when I don't feel right. I still blame the Shingrix Vaccine and wish I never took it. I have not proof but from reading others problems with the vaccine, and now afraid to take any of it. I think Big Pharma pushes junk without thorough testing! My opinion only and am still not better at all. Finally can walk somewhat without losing balance but not great. Think twice before taking shots. We took the flu shot and hubby and I both had pneumonia shots and he got pneumonia 2 years ago and this year we both got the flu and he got pneumonia again, and was hospitalized for the second time. Hope your wife gets will. Sorry this has happened to her.