Hi @ngyose, since you and your wife are dealing with early or young onset dementia (YOD), I also included this important topic in the Caregivers: Dementia group (https://connect.mayoclinic.org/group/caregivers-dementia/). You may wish to follow the group and join the discussions there.

@IndianaScott, did you have any issues of being bitten when using the fingertip tooth brush?

Ngyose, as you point out, dental hygiene is important for overall health. I found some of the tips in this article to be potentially practical
- Family Caregiver Alliance https://www.caregiver.org/dental-care-dementia
For example, breaking down instructions into steps and offering pieces of apple for those times when brushing wasn't successful. I was a bit surprised to read that flossing is more important than brushing. Did you realize that? Any of the tips resonate with you?