Good afternoon @curtj, Welcome to Connect. We are a community of patients, parents, providers, and caretakers, not medically trained but very experienced in what has happened in our bodies and what steps we have taken to move on from the diagnosed illness or condition. It appears that you are exploring information for your wife as written by another member, @cindy62 who had opened a discussion in October 2019. It is likely that @cindy62 is not active at this time. If you would like to find information neuropathy information go directly to:

Member Neuropathy Journey Stories: What's Yours?: https://connect.mayoclinic.org/discussion/member-neuoropathy-journey-stories-whats-yours/

You will find a post on the right-hand side of the heading. It will say Oldest......followed by Newest. So for the latest posts tap Newest. You will also find more than 100 different Discussions in the Neuropathy group listed when you click on Discussions. It might be best to go through them and see if any other discussions connect with your question.

What exactly is causing your wife the most serious symptom that is concerning you? I realize the dismay you must feel at not even getting a diagnosis. I think you might find help on Connect by using the search tool at the top right directly to the left of your photo. Type your keyword in the box and press the magnifying glass. Take a look.

I will be waiting for you to fill me in a bit more and then while you are searching the discussions, I can see just who might be lurking in the wings with a very similar journey and a happy outcome.

May you and your wife be free of suffering and the causes of suffering.
Chris

Hi Curt. It has been 21 months since I first had the viral illness that caused the neuropathy. I have never gotten another diagnosis other than Post Viral Neuropathy. The only abnormal test that I had was the presence of an antibody that they haven’t been able to identify. For a long time I worried that it was something else, but I finally accepted that diagnosis and decided to live with it. I was told that the nerves that are damaged from a viral antibody reaction may slowly regenerate. Or they may never get any better. My symptoms have improved somewhat albeit slowly and non-consistently. I still have some tingling in my feet and muscle cramps with twitching in my calves. My hands bother me the most, especially at night and early morning when they really burn. I exercise and do yoga daily - that helps. I took a low dose Amitriptyline for about a year. That helped quite a bit, but I didn’t like the side effects so I am tapering off of those. I hope your wife finds some answers and starts to improve. Know that it may take awhile but have her keep trying different things to feel better. Listening to other’s stories helps😊
Cindy