I was told this, too, but they're not the same -- look at the side effect profile. Plus regardless of drug class, whether antibiotics or biologics, they're different molecules! This makes me so angry. I was told my two different rheums that Orencia is believed to have a decreased risk of infection. Now, if I was the doc, I'd look at my patients file first. Hmmmm, Asthma, has had MRSA twice, I think i would have selected Orencia rather than putting the ball in the patient's court! I don't understand the laziness or if they're afraid to be sued, if a patient gets a bad side effect? Just guessing....