I have to deal with fatigue on a daily basis, too. I've accepted the fact that on most days I have to take a long nap. You do learn to plan for the fatigue. Last summer, my wife and I took an extended camping trip to the west coast (6 weeks). As we made plans, we made sure that our traveling days were not too long. And we usually made sure we stayed at each campground for at least 2 nights. That way, I had time to rest up if I needed it. @1nan , I never thought about mental fatigue before. But now that you mention it, I agree that it is real. Sometimes you need to shut down your mind and just do nothing. A couple of things that keep me going are singing old hymns at the retirement/nursing homes in our area and volunteering at our local hospital. I tell people that I've been a patient in just about every department, so I know my way around. During my chemo, I was there so often I asked if I could just buy a membership.