Hello Jim, I just started on Oxymorphone I hate the feeling. Very different from Hydromorphone. I feel confused, very slow, my husband doesn't like what he sees and said I look very drugged, I feel very drugged. He also said, from all these opiates he's frighted it will shorten my life. I'm so scared because I feel the same. My doctor never talks about the side effects, I'm afraid to bring it up because he makes me feel guilty because the pain is so bad. We think he's frustrated with me and he doesn't hide it. Hard to find care because of my diagnosis {drs caused it] HopeI'm making sense?