I was on Anastrozole for about 4 months and I broke out in some pretty severe hives. My doctors aren’t sure why I broke out with skin issues, but hives are a rare side effect of Anastrozole. So my oncologist switched me to Tomoxifin, 10 mg., and I’ve been fine. My worst side effect of both Anastrozole and Tomoxifin has been brain fog, and difficulties with memory. By googling those drugs and learning all I can about them, I have found that some memory and cognitive function problems are indeed a side effect. Since my cancer was a very slow growing type, my oncologist gave me a break from these drugs for about 4 months to see if it makes a difference. It’s night and day where my cognitive function is concerned! I absolutely hate not being able to think clearly!! I see Dr. Saundra Buys, my oncologist, again at the end of September and we’ll discuss what to do then. But if she feels that going back on meds. at that time is in my best interest, then I’ll follow her advise. She may advise an alternative medication, or some other solution. But I trust her judgement and know she has my best interest at heart. Cancer sucks!!!