I will be on Tirosint for the rest of my life but there hasn't been any uptake in my Tumor marker bloodwork or in any PET Scan since. If you KNOW something is wrong even if they tell you it all seems okay, find a doctor that will listen to you. Once I got the referral to Mayo I told the surgeon day one of the consult that I wanted my Thyroid removed because it was absolutely unmanageable since my Hashimoto's diagnosis and luckily I had enough history medically documented that it was automatically a viable option for me and we scheduled the surgery immediately.