Yes, I broke out with hives and had some nasty hives from Anastrozole; it seems I had an allergic reaction to it. It also caused some memory loss issues. Tomoxifin also caused memory/cognitive issues. My doctor prescribed Arimidex/Exemestane at my visit this past Tuesday as an alternative to those. But when I went to pick them up at the pharmacy I was charged $175, at my regular Walgreens pharmacy. I did not complete the purchase and am seeking info. on why they are so expensive. I’d rather go back to Tomoxifin and just put up with memory loss and cognitive issues!