@kathysway Kathy - you just need to be sure if you need any dental procedures, i.e. crown work, root canal, tooth implantation, etc., that that is completed and healed prior to Zometa. My oncologist said that jaw necrosis is very rare. My suggestion for you as well is to plan your Zometa about future vacations. I just had mine last month so that the following one would not interfere with Christmas or New Year's. You may or may not feel like you've had the flu for a few days, but plan your life around it. The IV doesn't take that long.