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High gastrin levels
I’m tagging @markbrinkley @mommyof6 @gulzar as they’ve spoken about gastrin levels. Here’s some information from Mayo Clinic:
"While elevated gastrin may indicate tumors in your pancreas or duodenum, it also can be caused by other conditions. For example, gastrin may also be elevated if your stomach isn't making acid, or you're taking acid-reducing medications, such as proton pump inhibitors. Because gastrin levels can fluctuate, this test may be repeated a few times.” https://www.mayoclinic.org/diseases-conditions/zollinger-ellison-syndrome/diagnosis-treatment/drc-20379046
You might be interested in reading another, more detailed explanation of gastrin and elevated serum gastrin levels: https://neurology.testcatalog.org/show/GAST
I can only imagine how frustrating it must be, to not get a firm diagnosis, @miliangy. As @hopeful33250 mentioned, would you be able to consult with a gastroenterologist?
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@miliangy gastrinomas are extremely difficult to locate even with excellent imaging. PPIs do elevate gastrin levels as you stated. If you have been treated for an extended period >6 months with ppi, you should have a men1 work up with an endocrinologist. The lesion on the pancreas should be studied further as well by a Gastro doc. Potentially you should consider a consult with a NET specialist as well. Keep pushing for more as you speak to your doctors.
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