It is going to depend. on what the treatment is. After my surgery for pancreatic cancer, the doctors at Mayo determined what I needed for chemo, but I needed a local oncologist to prescribe it. I had my chemo at my local hospital. The following year I had kidney problems. The infusion was a specialized medicine. No one locally would administer it so I had to go to Mayo in Rochester each week for treatment (a 4 hour drive).