This is the second time for BC with me and the only times I have had the CA 15-3 checked were when I had the surgeries (lumpectomy). It has been routine to have the CA 27-29 done for each appointment. The first time I had BC, my Dr just seemed to monitor me. The first oncologist I had this time around told me that the 40s was normal for me from checking my former records. That oncologist and I parted ways, and I went to a woman who was absolutely horrible. I had seen her once and she sent me for a nuclear bone scan because my blood work showed a two of the readings were outside the normal range, and also a full body CT scan because my tumor marker was 49. I insisted on having the test redone and 3 days later it was 41.8, but she still insisted. When I tried to ask her questions at my last appointment concerning the CT scan, she had her info all wrong and when I told her I had brought copies of my reports, she actually would not talk to me and ran out of the room. Oncologist #3 is, so far, amazing. I told him about the tumor marker stuff and he says he does not go by them as they change all the time. Also, if you read the comment that comes with your CA 27-29 that comes with your report it says “The CA27-29 assay is intended for use in monitoring: 1) disease progression and/or response to therapy in patients with metastatic disease, and 2) disease recurrence in patients treated previously for stages II and III breast carcinoma who are clinically free of the disease.” My cancer was stage 1 and so none of this applies and the CA 27–29 should not be used as a tool for diagnosing malignancy. Also, unnecessary tests are done that are expensive and that only frighten the patient. Also, it is my understanding that for the CA 27-29, the initial reading after surgery may be a bit high, but seems to decline after that. I really appreciate your response because it is good to hear of someone that also does not fit the slot doctors have put people in because it is easy and convenient for them. I also have gotten all my test results from the first time around and what I have so far this time so that I can understand and know what the doctor is talking about. You might want to do that. Doctors are not perfect and make mistakes and knowing what test results mean can help you in monitoring your own disease. Again, thank you for your reply.