@lampstone Pam, my Mayo dr said I would be on antibiotics for the rest of my life most likely. I have tested negative for mac since 2014; but caught pseudo in 2016 and went neg for that after 30 day treatment on tobramycin. My dr said that although I am negative for organisms, he is now treating the bronchiectasis, the condition that allows mac and pseudo to attack us. So, my meds now are taken for preventative measures. I also relocated geographically in 2012. I believe the exposure to mac is minimal where I live now. I know that the state of Va is not healthy for me. There is lots of dampness and rotting leaves there. That state and Arizona kept me ill; in coastal South Carolina, I have been mostly healthy and happy. Hope this helps.