I have been on Prozac , Effexor, Wellbutrin, lithium, Abilify . I am not bi-polar just diagnosed with sever depression. Both of my parents and their parents dealt with it. I’m not saying spravoto nasal spray is very controlled. I Have visited New Hope Specialty Care Charlotte, NC which is that type of controlled clinic. After treatment you are observed for 2 hours. Google Ketomine for depression 60 minutes . Everyone so far has had nothing but good results. People planning suicide have been AMAZED at the results. Now we must push the insurance companies. United Health Care supports this newe drug.