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Olaparib (trade name Lynparza), metformin and ovarian cancer

Gynecologic Cancers | Last Active: Jul 3, 2019 | Replies (7)
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@pauldale4

I was on Lynparza for 6 months with no side effects but my tumors metastasized so they took me off and I am currently on a clinical trial called TAPUR. Everyone reacts differently so what doesn’t work for one may work for another. Good luck.

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Replies to "I was on Lynparza for 6 months with no side effects but my tumors metastasized so..."
starko | @starko | May 3, 2019

I am so sorry to hear of your tumors metastasizing. I thought lynparza was meant to prevent that occurrence. Have you ( or your oncologist) considered metformin? NIH reports “metaformin treatment inhibits both angiogenesis and metastatic spread of ovarian cancer. “ You did not mention your particular type of cancer. I have ovarian stage IIIC.

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