Talk therapy works if you get the best psychiatrist to work with you. My last one was great and I learned how to deal with my very dark moods. I was in private therapy and also in group therapy. Both methods helped me, but I had to figure out how to deal with it on a daily basis. Clinical depression runs in my family on my mother’s side. It seems like is it genetic because so many family members have it. It starts in our teenage years. I have it, my son and granddaughter have it as well as several cousins and my niece and nephew. Several family members committed suicide. When I was in my twenties, I was a regular patient in the emergency room with overdoses. Group therapy is beneficial too. I learned how to change my brain and deal with my clinical depression. When I was hospitalized, I was put on Thorazine. I was in therapy with a psychiatrist for 15 years, so I understand about depression and how it affects your body. Yes, the intestines and stomach feel it too. I have had part of my large intestine removed. My last suicide attempt was 50 years ago, so I did get it under control, but I still get dark moods. I know how to get them out of my brain. I am a positive thinker now and look on the bright side of things. I don’t let myself fall into that pit of doom. It has been a struggle sometimes during those last 50 years, and I have had to help my son with his depression, but we are still here. My granddaughter sees her psychiatrist every week. She has been in therapy since she was 14 years old and has had several suicide attempts. We live with this disease but some of us have died. Okay, I wasn’t going to contribute to this thread because I am in charge of my brain and don’t suffer from this anymore, but I wanted you all to know that I understand how you feel.