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Can Gabapentin make neuropathy pain worse?

Neuropathy | Last Active: 2 days ago | Replies (374)

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@terrydclaar

I take 3600 mg of Gabapentin each day, but also take Mg supplement. This is the first I heard of Mg cancelling effect of the drug.
Is there a report on this in the literature?

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Replies to "I take 3600 mg of Gabapentin each day, but also take Mg supplement. This is the..."

Hello terrydclaar and @hotfooted, I am Sunnyflower. I hope you are going much better than tolerable today. I haven't been around too much lately and have missed tons of messages so please forgive if this is a repeat. I take Gabapentin as well but only recently am up to 900mg daily, 3-100mg. caps, three times a day. I have been on Gaba for about a year and a half. I have MANY of the unwanted side-effects and hate this drug, however, it helps me tolerate my pain. I MUST take magnesium b/c of the brutal muscle tetany I experience way too often for years. I don't have them in the arch of my foot nor my calves like most people rather on the tops of my feet, around my ankles, inner thighs, hamstrings and quads and then hands/fingers. I had it for 12 hours the other day. So many meds, homeostasis is off. I have increased my magnesium to 400mg, three times per day, last dose at bedtime. I read on Mayo Clinic that it's only Magnesium OXYBATE that can have an interaction with Gabapentin. I still can't sleep well and wonder if it's the Gaba??? I wish you all a blessed Christmas and a safe happy New Year. Many blessings, Sunnyflower

Hi Terry, I take 400mg. magnesium and gabapentin 1xday 300mg. for 3 years and have never experienced any less effectiveness of gabapentin. Helen