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Can Gabapentin make neuropathy pain worse?

Neuropathy | Last Active: 16 hours ago | Replies (363)
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@jmicoumiller48

My neuropathy has been getting worse. I am a diabetic type 2 and I take gabapentin 300 mg twice a day, however I have been having to take 600 mg two tablets before bedtime. I am convinced that the increased dosage is contributing to worsened neuropathy.
Best regards,
Jim Miller

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Replies to "My neuropathy has been getting worse. I am a diabetic type 2 and I take gabapentin..."
John, Volunteer Mentor | @johnbishop | Oct 26, 2020

Hello @jmicoumiller48, Welcome to Mayo Clinic Connect. I'm not sure it makes it worse, it's just that gabapentin (neurontin) is a seizure medication and treating neuropathy is one of the drugs prescribed for off label use - neuropathic pain being one of them. Not sure it this is helpful but may give you an understanding that you are not alone.

Neurontin: Over-Hyped And Underwhelming: https://www.acsh.org/news/2017/12/26/neurontin-over-hyped-and-underwhelming-12242

You may also be interested in another discussion where members have shared their neuropathy stories - Member Neuropathy Journey Stories: What's Yours?: https://connect.mayoclinic.org/discussion/member-neuoropathy-journey-stories-whats-yours/

Are you able to share more about your neuropathy diagnosis? Is it diabetic neuropathy?

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Leonard | @jakedduck1 | Oct 26, 2020

@jmicoumiller48
Hello Jim,
Why are you taking 600mg at night? How long have you had Neuropathy? Are you having any side effects from the medication?
Take care,
Jake

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