@sundance6 I have fibromyalgia Dr put me on 300mg ,awful experience I forgot where I was ,scary so I didn't take anymore Talked with my PCP she tried me on 100mg took it for a week at bedtime then noticed how it was doing same thing .I told her what it was doing g she stopped it So not on anything g now accept my Magnesium 500 mg so far so 👍 That's my experience so everyone is different I have never been able to take high dosages .