← Return to Living with Prostate Cancer: Meet others & introduce yourself

Discussion
Comment receiving replies
@waynen

Some people on this thread have asked questions about biopsys. This recent study might help in looking at the traditional 12 sample transrectal biopsy done by many urologists and the mMRI Targeted biopsys. It's clear from the research that, if you can get it, the mMRI is a better choice.

The authors of this multicenter, randomized, noninferiority trial compared magnetic resonance imaging (MRI)–targeted biopsy with the standard systematic 12-core transrectal ultrasonography (TRUS) biopsy procedure in men with clinical suspicion of prostate cancer. MRI-targeted biopsy in men with a PI-RADS score ≥3 was noninferior to standard TRUS biopsy, with the detection of clinically significant prostate cancer in 35% of patients undergoing MRI-targeted biopsy versus 30% with the TRUS biopsy. In addition, 37% of patients in the MRI-targeted group were able to avoid prostate biopsy due to low PI-RADS score.

These results indicate that MRI-targeted biopsy procedures may allow for fewer prostate biopsy procedures with similar rates of detection in men with clinical suspicion of prostate cancer.
– Emily Miller, MD

Jump to this post


Replies to "Some people on this thread have asked questions about biopsys. This recent study might help in..."

Can you possibly post results of further studies into the pros and cons of each procedure. I am about to have transrectal 18 needle biopsy as the preference of my urologist. This even though I suggested MRI and targeted biopsy if anything suspicious was noted. PSA 8 now. Two years ago had MRI that scored 2 out of the 5 point rating for likelihood of cancer (ignorant of this except 1 is best for no cancer). At that time PSA was 6. Mine has always run high at 5+. Age 74

I am scheduled for Transperineal biopsy on March 5th. MRI found 2 lesions one with PIRADS score of 5 and the other with a score of 4. Should I get a targeted biopsy at those 2 locations only or also additional 12 core random biopsies also or just go along with whatever my urologist recommends?