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@horace1818

I faced the same decision as you and Dave in 2016 and chose surgery. It is an intensely personal and emotional decision but here are some of the considerations:
I was Gleason 7 and cancer cells had probably not escaped the capsule; PSA was 12+ and was doubling every year; I was 74 and in good condition with the prospect of many years of life however, I had just watched a close friend die of prostate cancer and it was not pretty. I had to take some action. Review of the literature, especially the Harvard Annual Review of prostate cancer, confirmed that we really don't know much about prostate cancer and that the available therapies were fraught with awful side effects. The available drugs are for advanced prostate cancer and radiation is non-specific and kills all in its path; incontinence and impotence are common and the prospect for a cure much less than with surgery.
The genetic evaluation on my fresh biopsy tissue came out at 5 on a scale of 10 so was not much help (this is based on an algorithm developed by following several thousand men and looking for genes that are common in fatal and recovered cases - the data base is small and so not reliable). So that left surgery or watchful waiting. The trouble with waiting was that if it continued to grow, I would soon be too old for surgery and once it breaks out of the prostate and metastasizes the chance of a cure with existing therapies is low and surgery is no longer an option.
Surgery had a high chance of a complete cure with the downside being possible incontinence and/or a severely impaired sex life. But the alternatives were worse and so, after talking to some men who had done it, I opted for surgery. It was done at Mayo on a daVinci and turned out well. The surgeons were great! I am now 3.5 years post-op with a PSA still undetectable. The cancer seems to be cured but it won't be declared so until 5 years. Adverse effects are some very minor leakage that is easy to manage, an inguinal hernia 4 months post-op (caused by blowing you up with CO2 for the duration of the surgery so the micro instruments can get to your parts) that has been surgically fixed, some ongoing chronic urethral pain (2-3 on the 10 pain scale, can live with it) and ED. The ED is a problem with all surgery and your sex life will never be the same, but it is not bad, just different. You will have to use ED drugs or devices. But I will take that in return for a cure. One bonus is an increased urine storage capacity and a very strong stream; BPH is gone forever!!
Any time that cancer can be cured by surgery, it is a good idea to do it. I like the idea of a long life without prostate cancer.
Hope this helps.

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Replies to "I faced the same decision as you and Dave in 2016 and chose surgery. It is..."

Thanks for all the detailed info! As I said in another post, everyone has a different story and different reasons for how they approach treatment and I'm glad you found what worked for you! There is much in your email that has gone into my similar thinking. In particular your little section on radiation and also surgery as a chance of a cure is kind of where I am at on that. I would rather not do anything but unfortunately have passed that stage and can't wait for the next generation cures so have to work with what is here now. I'm Gleason 7 (3+4), and PSA is 8.7 at the latest. I've only gone up about 1 point in the last year which is good but with the Genomic test added they think I should act. I'm about 2/3 up the scale on that......... I've been taking LOADS OF SUPPLEMENTS for a year, some on advice of a cancer naturopath and some from what I've picked up here and there so that may be a factor in the slow rise. Many have been studied with cancer in mind and some have had research studies done and published. In any event even if they are not stopping the cancer, they are really good for the immune system. Naturopath says ALL MUSHROOMS are good (store or wild) (either eaten for the beta glucan or supplements), Stamets 7 has 7 diff. cancer related mushrooms in 1, also Chaga Tea for drinking or Chaga alcohol extract by dropper, Curcumin/Turmeric, Melatonin, POMI-T supplement. The supplements can also be taken continually after to help slow or mitigate future returning cancer. The Naturopath unfortunately does not have a magic cure but works with health and immune system before and after treatment which he also recommends doing.