Jennifer, I have studied the literature on the anticoagulants and remain committed to Warfarin (Coumadin). When I started on it, it was the only anticoagulant that had a ready antidote. That became crucial to me after a friend and neighbor on Warfarin died when the ER to which he was taken by public ambulance had no Warfarin antidote on hand, so they called for a helicopter to take him to another hospital. He died enroute from a brain bleed. I sang at his funeral.

There are now two anticoagulants for which antidotes are on hand in ERs that care about the quality of their life-and-death services -- for Warfarin and Pradaxa. No antidote for Eliquis has yet been approved by the FDA.