Letrozole: When will I start feeling/seeing side effects?

I'm on Letrazole, also. If you're not having side effects, that's great. I started having side effects with in 24 hours of starting the meds, but I already had some joint issues! Acupuncture, Yoga, Mindfulness and Ibuprofen all work. I also found out I was Vitamin D3 deficient which also contributes to the pain. I am considering switching to another AI when this refill comes due.

tammy, I am 6 weeks in and lots of joint Pain and i already had arthritis and this is making it worse. I do Yoga and have been taking D3 for years. What AI are you considering switching too. The other options sound much worse

@tammyp @francine6829 - From what I've read so far on this and other sites, pretty much all the AI drugs have some potent side effects I've been on Arimidex for 14 months. I've preciously listed my side effects here and I think I just have to stick with it for the 5 years. I don't like to take Ibuprofen much, but I do when the pains get intolerable.

That last post of mine should read "I've PREVIOUSLY listed", not preciously listed! :):):)

Hi. I've been on arimidez for about a month now and aside from having a hard time falling asleep and the odd ache in my legs, I think I'm tolerating it well. I'm hoping as time goes by the side effects don't worsen or appear. One question though, since starting the AI I have started having pain and weird twinges in my breast that I had surgery on. Has anyone else experienced this? I'm wondering if it's because my estrogen levels are pretty much nil now. Thank you all.

@karendb - Karen, yes, I've had that. Not severe pain, but sensitivity and small twinges of pain. My Oncologist said that can go on for a long time, sometimes years.

I'm not sure. My Oncologist stated it may be how a particular AI is compounded, that causes the side effects. I've got to look at my Genetic Pharmacology Report to help me determine how to proceed.

@sparklegram thank you so much for answering me. I see my surgeon tomorrow for follow up and will mention it to her as well. Hopefully I was just letting that old horrible fear demon get to me again and it's what you said. I'll be sure to let you know.

Genetic Pharmacology Report?

@francine6829, here is some information about pharmacogenomic testing (PGx) http://mayoresearch.mayo.edu/center-for-individualized-medicine/pharmacogenomics-pgx.asp#what-is-pharmacogenomics-pgx

In brief: "PGx is the study of how your genes may affect your body’s response to, and interaction with, some prescription or over-the-counter medications. Genes, which are inherited from your parents, carry information that determine characteristics such as eye color and blood type. Genes can also influence how you process and respond to medications. Depending on your genetic make-up, some medications may work faster or slower, or produce more or fewer side effects."