JK - Long term or repeated use of oral steroids (like my daughter has used for years for intractable asthma, or my friend used for RA) is one of the culprits in osteoporosis, even though the daily dose is relatively low. I learned it years ago, and have never been willing to stay on prednisone except during acute asthma or bronchitis because we have a 4 generation history of significant osteoporosis. My daughter is being switched from prednisone to a biologic for her asthma. So far, in spite of everything, my bone density looks quite good, but hers is beginning to show early osteopenia at only age 40.
Sue