Hello @italapino, Welcome to Mayo Clinic Connect. I have small fiber peripheral neuropathy. Some of your symptoms sound like small fiber neuropathy but I have no medical training or background and cannot give any advice on diagnosing conditions other than sharing my own personal experience. I'm glad to see you have already have an upcoming appointment at the Mayo Clinic Arizona Campus for a second opinion where you will be in good hands for coming up with a diagnosis and treatment plan. Mayo Clinic is very good at diagnosing and treating difficult to diagnose health conditions.

There is another active discussion on small fiber neuropathy where your post will have more visibility. I'm tagging our moderator @lisalucier to see if we should move your post to the following discussion so other members with small fiber neuropathy will see your post and be able to share their diagnosis and treatment.

Groups > Neuropathy > Small Fiber Neuropathy
-- https://connect.mayoclinic.org/discussion/small-fiber-neuropathy-1/

In my personal experience with small fiber peripheral neuropathy, it started in the toes of both feet and progressed over the past 20+ years to the lower part of both legs when I decided to have it diagnosed in 2016. There wasn't an urgency on my part because I didn't have any pain. I only had the tingling and numbness symptoms. I'm really glad that you are taking the steps early to get a diagnosis and treatment plan.

@roch shared some great tips here on how to get off to a a best start with a new specialist in another discussion that may help you prepare for your upcoming Mayo appointment:
-- https://connect.mayoclinic.org/discussion/your-tips-on-how-to-get-off-to-the-best-start-with-a-new-specialist/?pg=1#comment-240765

I thought this link to Becoming a Patient at Mayo Clinic's Campus in Arizona might also be helpful:
-- https://www.mayoclinic.org/patient-visitor-guide/arizona/becoming-a-patient

Can you share an update with us on your diagnosis after your Mayo appointment?