I have Primary Antibody Deficiency. I am deficient in IgG and IgM. I am treated with 35 grams of Immunoglobulin infused by a nurse, every 4 weeks.
The restores my antibody level and I no longer am sick all the time. I will have this IVIG for life.

Unfortunately my deficient Immune System ALSO ATTACKS the organs and systems of my body, primarily my nerves causing neuropathy. I have profound peripheral neuropathy affecting my lower legs and feet. I am completely disabled, wear leg braces, and walk with a walker. My lower legs have atrophied significantly. I also have severe Small Fiber Neuropathy which is reasonably controlled by 4200 mg Gabapentin daily.

My moisture system (tears and saliva), my lungs, my bladder, my hearing and my gastrointestinal system have all been attacked by my Immune System, nerve damage resulting. My Duke Research Immunologist, who specializes in my Immune Disorder, says that my Immune Systems uses Cytokines to attack my body. My husband is also a Research Immunologist, and he agrees with this diagnosis.

There is no treatment for the attack by my Immune System on my body, unfortunately. When my Immune System is carrying out an attack this causes an Inflammatory Response. Inflammation causes Pain, Fatigue, and Depression.

Because I also have severe Osteoarthritis (knees, hips, shoulders, neck and hands) I experience severe pain during these Inflammatory Attacks.

Ain't We Got Fun?!

Regards, ElaineD