Hi @beatitnow, I was on Amikacin Inhaled for a year. I have new nodules but apparently they can come and go. My recent Bronch sample came back clear of MAI. I think we are all learning incl the drs. Unfortunately nothing much is confirmed about MAI but we can help that with this site. I am not sure that there is a time that MAI re flares, everyone seems to be different, I know Quite a few at 2 years and I have been told there was a lady whos reflared at 15 years(very unusual). Hopefully we can all be successful at taking meds that do not do us much damage but keep the MAC at bay like @windwalker. There is alot in the pipeline, bring it on. If you take inhaled Amikacin let me know and I can help.