Everyone reacts differently to gabapentin; I was originally prescribed 100 mg. 3xday but I couldn’t remember anything after 1 day so I cut back to 1x at bedtime and after almost 3 yrs. have increased it 2 times, now take 300 mg. at bed (sometimes 400 if having a flare) and I am good for 24 hrs. I read somewhere that less is more with gabapentin and that has been true for me. It seems like most drs. like to start off prescribing a regimen of 3xday when it may not be necessary. I have noticed my neuropathy has worsened over the last few months but I prefer not to increase my dosage because of the memory problems. Helen