Hi, @alanism - I'd like to add my welcome to Mayo Clinic Connect. I'm sorry to hear about the spike in anxiety, and that you are not liking the new house you've moved into. In this stress inventory, you'll note that moving house is among the top 30 stressors https://www.stress.org/holmes-rahe-stress-inventory/. Thus, very understandable.

We have a number of members who have mentioned alprazolam (Xanax) before, so I'd like to invite some of them into this conversation so they can share their experiences. Please meet @dianrib @annedodrill44 @pankaj @montana_mom8 @soliloquized @margot69. @gailb may also have some thoughts for you.

You might also check out this discussion on one of the brand names for sertraline, Zoloft https://connect.mayoclinic.org/discussion/peoples-opinions-on-zoloft.

Has your doctor indicated for how long he or she wants you to take the alprazolam (Xanax)? Did they mention a taper at some point when the sertraline is having its full effect?