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Small Fiber Neuropathy?

Neuropathy | Last Active: Feb 12, 2023 | Replies (214)

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@jimhd

@chase61

I started taking Imipramine around six weeks ago, and it's been making a difference. Unfortunately, the interactions with other meds I take has moved my blood pressure from my life long reading of 120/60 to 160/100. I'm trying to taper off the other meds one at a time to try to find the culprit. So far, I'm off morphine sulfate contin and last night I started going off Mirtazapine, which is an add on antidepressant. Since Imipramine is also an antidepressant, perhaps I won't need it if I can keep taking Imipramine. I finished getting off the ms contin 4 days ago, but so far no change in my BP. For me, taking meds has been an ordeal of trial and error.

Jim

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Replies to "@chase61 I started taking Imipramine around six weeks ago, and it's been making a difference. Unfortunately,..."

@jimhd
My uneducated opinion is not to expect a decrease in blood pressure as long as your taking a
Tricyclic antidepressant.
Try stopping your Imipramine. Bet ya a nickel your pressure goes down. When did it start to increase?
Jake

I have taken imipramine on and off over the last 30years. Early in my life made a huge difference. Have taken it with cymbalta low dose bu came off the cymbalta 6 months ago. May try to add on again.