Hi Jager5210, yes, the R-Ala is supposedly the one that is beneficial although the brand I take (Dr. Danielle’s) Amazon has both R and S. I tried stopping it once and did notice a difference in my pain level. I also tried B12, BComplex, benfotiamine and acetyl-l-carnitine which I felt did nothing for me, I actually thought the B12 made my pain worse. I have not tried other brands but there are probably comparable but less expensive brands available. Hope this info helps.