@parus My Dr. prescribes Tramadol 50 for me doesn't have any problems They did require the Dr. to fax it at first but now she just calls it in. In face I called the other day for a renewal and they filled it. Now it maybe since I fractured my back I have been on it I only take 1 or 2 depending on how I fell . Have you asked your Dr. about this? Dr. also knows I have fibro and O.A. Tell the Dr. about your pain and why you have it with your problems don't just tell her about your depression/anxiety problem this a separate thing.