Hi Hank, So sorry to hear your wife has not had good results. When I went to my 3rd week on the highest setting I had to back off to the 2nd setting. 3 was just too high for me. It did actually cause me pain. It must over stimulate the nerves too much.???? I have to use the Laser TRX pretty much every day. I do miss a day or so every now and then and my pain returns, but not to the level it was before. Thank goodness. So sorry she is now suffering possibly more. I really wanted this to work for her. Please give her my best and my continued prayers for a healing or at least a major relief.