@drpepper l was put on xifaxan for liver disease and it's really for constipation to help you excrete toxins out of your body especially when you can't do it naturally. The first time l was placed on it l vomited the whole next day. Then l didn't want to take it anymore. I was already on the disgusting lactulose but the doctor told me they work better together. So l gave it another try and l tolerated it fine. I take it twice a day.