I’m taking Duloxetine and Trintellux together. Trintellix was added to my arsenal about 1 month ago. I’m on a low dosage of 10mg. I too have been taking Triintellix in the morning but wonder how f night time is best. I started off at 5 mg but can’t really tell that it’s working. I’ve not really noticed any side effects. Any ideas out there? I take 90mg of Dulixetine and have for years. I’m wondering how long it typically takes for the Trintellix to take effect if I s going to be affective for me.