Hello, @debravalentina, and welcome to Mayo Clinic Connect. You'll note I moved your post to this existing discussion, "Weaning off Effexor with CBD Oil," so that you can Connect with others who have had similar experiences.

I'd suggest talking to your doctor about your wishes to wean off of this medication to get a tapering schedule and to get some input on utilizing CBD oil in this process. I'd also like you to meet @ang811 @merpreb @mrossano @parus @grandmar and others for some thoughts and support on your journey.

Wondering how the venlafaxine has gone for you and if you'd share more about why you hope to taper off of it at this point?