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tim1028 (@tim1028)

Side Benefits of Statins

Heart & Blood Health | Last Active: Dec 21, 2018 | Replies (6)

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@kanaazpereira

Hi @tim1028,

I really appreciate the time you’ve taken to write about the benefits of statins. I particularly like the first point about "Improved or restored endothelial function (by nitric oxide biosynthesis)” I’d also like to explain why I feel there may be some discrepancies in this list.

Whenever claims or opinions about medical/health issues are made, it’s best to validate and support those with a citation or published studies. For example, the following notes…
– Protects cardiovascular cells directly by speeding DNA repair and slowing cell death
– Increased expression of atheroprotective genes
…are mainly theoretical, and haven’t yet been established by any clinical trials or studies.

Also, some other points about statins in the list – 50% decreased heart attack and stroke risk – Reversal of negative effects on heart – may be a bit exaggerated. I couldn’t find much online to confidently state that.

@tim1028, please feel free to let me know if I can help answer any questions or concerns you might have. Thank you for allowing me to add my thoughts to your post which, as I noted, has some good information; statins have obtained a "bad reputation" when it comes to side effects, despite the fact that benefits outweigh the risks.

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Replies to "Hi @tim1028, I really appreciate the time you’ve taken to write about the benefits of statins...."

Thanks for your reply. I have included a link to an published study related to statins and atheroprotective genes
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482202/