I have been diagnosed with IBS and am in the elimination phase of the low FODMAP diet. I never know when I am going to have abdominal cramps and/or diarrhea or what is causing them. There are other FODMAPS besides fructose that contribute to IBS. I also have GERD, which has been a problem for me for years. The medications may have contributed to developing IBS as a couple of people have mentioned, but at this point my reflux problem has become worse. I am taking a larger dosage of Nexium, plus sucralfate and am still having problems at night. This is truly miserable!