I had s similar experience. About a year and a half ago I just had a couple nodules. I started getting immuniglobulin infusions for my Immunodeficiency. There was no growth for awhile. Suddenly it just started getting active. I am showing inflammation in both lungs now and new tree and bud growth. I also started getting other types of infections. I tried the big three several months ago but could"nt tolerate it. It was highly recommended that I try again because I coughed up some blood. I was referred to UCLA and was scheduled for the day after Christmas. I am also scared but I really need to get through this antibiotic treatment. I had vision problems while on Ethambutol and pretty bad cramps and diarrhea. If anyone has any recommendations for the gastrointestinal side effects I would appreciate hearing them.